SML0452
AZ513
≥98% (HPLC)
Synonym(s):
2,3-Dichloro-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide
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About This Item
Empirical Formula (Hill Notation):
C14H9Cl2N3O
CAS Number:
Molecular Weight:
306.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C14H9Cl2N3O/c15-11-3-1-2-10(12(11)16)14(20)19-9-6-8-4-5-17-13(8)18-7-9/h1-7H,(H,17,18)(H,19,20)
SMILES string
Clc1cccc(C(=O)Nc2cnc3[nH]ccc3c2)c1Cl
InChI key
SIMLBFHHXAMGGM-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 15 mg/mL (clear solution)
storage temp.
2-8°C
Biochem/physiol Actions
AZ513 is a reversible, noncompetitive FAAH inhibitor.
AZ513 is a reversible, noncompetitive FAAH inhibitor. It also binds non-competitively at a site distinct from the catalytic site. AZ513 is 20-fold more potent against rat FAAH (IC50 27 nM) than the human form (IC50 551 nM).
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