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SML0475

Sigma-Aldrich

CGP36742

≥97% (NMR)

Synonym(s):

P-(3-Aminopropyl)-P-butyl-phosphinic acid, SGS 742

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100 G
CN¥664.69
500 G
CN¥2,343.68

CN¥664.69


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100 G
CN¥664.69
500 G
CN¥2,343.68

About This Item

Empirical Formula (Hill Notation):
C7H18NO2P
CAS Number:
Molecular Weight:
179.20
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

CN¥664.69


In StockDetails


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Quality Level

Assay

≥97% (NMR)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 10 mg/mL (clear solution, warmed)

storage temp.

room temp

SMILES string

CCCCP(O)(=O)CCCN

InChI

1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10)

InChI key

ONNMDRQRSGKZCN-UHFFFAOYSA-N

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This Item
403040V900190300060
form

powder

form

-

form

powder or solid

form

powder

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

-

application(s)

-

application(s)

-

solubility

H2O: soluble 1 gm in 0.35ml, acetone: very soluble, alcohol: slightly soluble (Dehydrated), benzene: insoluble, carbon tetrachloride: insoluble, diethyl ether: insoluble, petroleum ether: insoluble, glycerol: soluble 1gm in 1 ml (warm), alcohol: very soluble, chloroform: insoluble, alcohol: freely soluble (Diluted), hexane: insoluble, carbon disulfide: insoluble

solubility

-

solubility

-

solubility

-

grade

puriss.

grade

-

grade

-

grade

-

impurities

dextrines, gum matters, in accordance, ≤0.003% heavy metals (as Pb), resinous matters, in accordance

impurities

-

impurities

-

impurities

-

Biochem/physiol Actions

CGP36742 is a GABAB receptor antagonist.
CGP36742 was the first orally active GABAB-selective antagonist. The IC50 for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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