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SML0507

NPC26

≥98% (HPLC)

Synonym(s):

4,5,6,7-Tetrahydro-5,5,7,7-tetramethyl-2-[[(5-nitro-2-thienyl)carbonyl]amino]-thieno[2,3-c]pyridine-3-carboxylic acid ethyl ester, NPC-26

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About This Item

Empirical Formula (Hill Notation):
C19H23N3O5S2
CAS Number:
864860-32-2
Molecular Weight:
437.53
NACRES:
NA.77
PubChem Substance ID:
329825516
UNSPSC Code:
12352200
MDL number:
MFCD04428321
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

light orange to dark orange

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CCOC(=O)c1c2CC(C)(C)NC(C)(C)c2sc1NC(=O)c3ccc(s3)[N+]([O-])=O

InChI

1S/C19H23N3O5S2/c1-6-27-17(24)13-10-9-18(2,3)21-19(4,5)14(10)29-16(13)20-15(23)11-7-8-12(28-11)22(25)26/h7-8,21H,6,9H2,1-5H3,(H,20,23)

InChI key

DWGSXNATVAGHKZ-UHFFFAOYSA-N

Biochem/physiol Actions

NPC26 induces mitochondrial fragmentation and cell death in RAS expressing cells, similar to erastin. The effects of NPC26 are independent of ROS scavengers, which can block cell death induced by erastin.
NPC26 induces mitochondrial fragmentation and cell death in RAS expressing cells.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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