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SML0511

GNF-5

≥98% (HPLC)

Synonym(s):

N-(2-Hydroxyethyl)-3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

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About This Item

Empirical Formula (Hill Notation):
C20H17F3N4O3
CAS Number:
778277-15-9
Molecular Weight:
418.37
NACRES:
NA.77
PubChem Substance ID:
329825520
UNSPSC Code:
12352200
MDL number:
MFCD16877246
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

OCCNC(=O)c1cccc(c1)-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2

InChI

1S/C20H17F3N4O3/c21-20(22,23)30-16-6-4-15(5-7-16)27-18-11-17(25-12-26-18)13-2-1-3-14(10-13)19(29)24-8-9-28/h1-7,10-12,28H,8-9H2,(H,24,29)(H,25,26,27)

InChI key

IIQUYGWWHIHOCF-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

BRC-Abl inhibitor
GNF-5 is a BRC-Abl inhibitor.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Abl page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

GNF-5 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the GNF-5 probe summary on the Chemical Probes Portal website.

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000449659
0000449659
0000090867
092M4628V

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Articles

Discover Bioactive Small Molecules for Kinase Phosphatase Biology

Discover Bioactive Small Molecules for Kinase Phosphatase Biology

Global Trade Item Number

SKUGTIN
SML0511-25MG04061833223079
SML0511-5MG04061833223086

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