SML0623
Iniparib
≥98% (HPLC)
Synonym(s):
4-Iodo-3-nitrobenzamide, BSI-201
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About This Item
Empirical Formula (Hill Notation):
C7H5IN2O3
CAS Number:
Molecular Weight:
292.03
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear
storage temp.
room temp
InChI
1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11)
InChI key
MDOJTZQKHMAPBK-UHFFFAOYSA-N
General description
Iniparib is also called as BSI-201. It is an anticancer agent.
Biochem/physiol Actions
4-iodo-3-nitrobenzamide, the intracellular metabolite of iniparib has the capability to covalently prevent PARP1 (poly(ADP-Ribose) polymerase 1) under cell-free conditions. PARP inhibitor also plays a role in BRCA (breast cancer susceptibility protein) deficient tumors.
Iniparib (BSI-201) is an antineoplastic originally thought to be a poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor. Recent studies indicate Iniparib is not a PARP-1 inhibitor, and its mechanism of action is currently unknown.
Iniparib (BSI-201) is an antineoplastic.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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