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Merck
CN

SML0686

Talampanel

≥97% (HPLC)

Synonym(s):

(R)-(-)-1-(4-Aminophenyl)-3-acetyl-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine, GYKI 53773, LY 300164, LY300164

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About This Item

Empirical Formula (Hill Notation):
C19H19N3O3
CAS Number:
Molecular Weight:
337.37
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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InChI

1S/C19H19N3O3/c1-11-7-14-8-17-18(25-10-24-17)9-16(14)19(21-22(11)12(2)23)13-3-5-15(20)6-4-13/h3-6,8-9,11H,7,10,20H2,1-2H3/t11-/m1/s1

SMILES string

C[C@H](C1)N(C(C)=O)N=C(C2=CC=C(N)C=C2)C3=C1C=C(OCO4)C4=C3

InChI key

JACAAXNEHGBPOQ-LLVKDONJSA-N

assay

≥97% (HPLC)

form

powder

optical activity

[α]/D -280 to -340°, c = 1 in methanol

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

2-8°C

Quality Level

Biochem/physiol Actions

Talampanel ia a specific noncompetitive AMPA receptor antagonist and anticonvulsant.
Talampanel is a specific noncompetitive AMPA receptor antagonist; anticonvulsant.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Skull and crossbonesEnvironment

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Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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