SML0698
CID 11210285 hydrochloride
≥98% (HPLC)
Synonym(s):
2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine hydrochloride, AMBMP, N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride, Wnt Agonist
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About This Item
Empirical Formula (Hill Notation):
C19H18N4O3 · HCl
CAS Number:
Molecular Weight:
386.83
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
N(Cc3cc4c(cc3)OCO4)c1nc(nc(c1)c2cc(ccc2)OC)N
InChI
1S/C19H18N4O3/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16/h2-9H,10-11H2,1H3,(H3,20,21,22,23)
InChI key
FABQUVYDAXWUQP-UHFFFAOYSA-N
Application
CID 11210285 hydrochloride has been used as a Wnt agonist.
Biochem/physiol Actions
CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β. CID 11210285is a Wnt agonist.
CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β.
Other Notes
Light sensitve and air sensitive.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
Regulatory Information
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Amalia Rosner et al.
Developmental biology, 448(2), 320-341 (2018-11-06)
Inhibitors of Apoptosis Protein (IAP) genes participate in processes like apoptosis, proliferation, innate immunity, inflammation, cell motility, differentiation and in malignancies. Here we reveal 25 IAP genes in the tunicate Botryllus schlosseri's genome and their functions in two developmental biology
The activation of Wnt signaling by a STAT6-dependent macrophage phenotype promotes mucosal repair in murine IBD.
Cosin-Roger J, et al.
Mucosal Immunology, 9(4), 986-986 (2016)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML0698-5MG | 04061832824802 |
| SML0698-25MG | 04061832824796 |