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SML0710

DDRI-18

≥98% (HPLC)

Synonym(s):

3,3′-[6,6′-bi-1H-Benzimidazole]-2,2′-diylbis-benzenamine

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About This Item

Empirical Formula (Hill Notation):
C26H20N6
CAS Number:
4402-18-0
Molecular Weight:
416.48
NACRES:
NA.77
PubChem Substance ID:
329825588
UNSPSC Code:
12352200
MDL number:
MFCD01137750
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL

storage temp.

2-8°C

SMILES string

NC1=CC=CC(C(N2)=NC(C=C3)=C2C=C3C4=CC5=C(C=C4)N=C(N5)C6=CC(N)=CC=C6)=C1

InChI

1S/C26H20N6/c27-19-5-1-3-17(11-19)25-29-21-9-7-15(13-23(21)31-25)16-8-10-22-24(14-16)32-26(30-22)18-4-2-6-20(28)12-18/h1-14H,27-28H2,(H,29,31)(H,30,32)

InChI key

QROWVLFOWUYBIG-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin.
DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

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Certificates of Analysis (COA)

Lot/Batch Number
0000014243
053M4613V

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Global Trade Item Number

SKUGTIN
SML0710-25MG04061833025789
SML0710-5MG04061833025796

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