SML0756
IDT307
≥98% (HPLC), DAT, NET and SERT substrate, powder
Synonym(s):
4-(4-Dimethylamino)phenyl-1-methylpyridinium iodide, 4-[p-(Dimethylamino)phenyl]-1-methylpyridinium iodide, APP+
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About This Item
Empirical Formula (Hill Notation):
C14H17N2 · I
CAS Number:
Molecular Weight:
340.20
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Product Name
IDT307, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
, orange to dark orange-red
solubility
DMSO: 15 mg/mL, clear
storage temp.
−20°C
SMILES string
[I-].[n+]1(ccc(cc1)c2ccc(cc2)N(C)C)C
InChI
1S/C14H17N2.HI/c1-15(2)14-6-4-12(5-7-14)13-8-10-16(3)11-9-13;/h4-11H,1-3H3;1H/q+1;/p-1
InChI key
CAMWVBRDIKKGII-UHFFFAOYSA-M
Biochem/physiol Actions
IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+.
IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+ monoamine transporter substrate that fluoresces after uptake into cells. IDT307 is a substrate for the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). IDT307 (APP+) was found to label catecholamine neuronal cell bodies with high selectivity in midbrain and was used to investigate SERT function in lymphocytes and platelets.
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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