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Merck
CN

SML0775

PZ-II-029

≥98% (HPLC), a6b3g2/3g2-specific GABAA positive modulator, powder

Synonym(s):

2,5-Dihydro-7-methoxy-2-(4-methoxyphenyl)-3H-Pyrazolo[4,3-c]quinolin-3-one, 7-Methoxy-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one, PZII-029

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About This Item

Empirical Formula (Hill Notation):
C18H15N3O3
CAS Number:
164025-44-9
Molecular Weight:
321.33
UNSPSC Code:
12352200
NACRES:
NA.77

Key Documents

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Product Name

PZ-II-029, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

Related Categories

Biochem/physiol Actions

PZ-II-029 is an a6b3g2/3g2-specific GABAA positive modulator.
PZ-II-029 is the first compound to be identified as a specific postitive modulator of GABAA channels composed of α6β3γ2 subunits.

Features and Benefits

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000427124
0000427124
0000379875
0000379875
0000137482

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