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Merck
CN

SML0776

Galloflavin

≥95% (HPLC)

Synonym(s):

3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione, NSC 107022

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About This Item

Empirical Formula (Hill Notation):
C12H5O8
CAS Number:
Molecular Weight:
277.16
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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Quality Segment

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

light yellow to light brown

solubility

DMSO: 5 mg/mL, clear

storage temp.

−20°C

SMILES string

OC1=C(O)C(O)=CC2=C1C3=C(C=C(O)C(O3)=O)OC2=O

InChI

1S/C12H6O8/c13-4-1-3-7(9(16)8(4)15)10-6(19-11(3)17)2-5(14)12(18)20-10/h1-2,13-16H

InChI key

VYKVZHXHVUVABA-UHFFFAOYSA-N

Biochem/physiol Actions

Galloflavin is an inhibitor of lactate dehydrogenase (LDH).
Galloflavin is an inhibitor of lactate dehydrogenase (LDH). The compound blocks both isoforms of (LDH-A and –B) with Ki values of 5.5 and 15 μM, respectively. Inhibition of the glycolytic pathway by galloflavin induces oxidative stress and apoptosis in breast tumor cell lines.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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