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Merck
CN

SML0876

Filastatin

≥98% (HPLC)

Synonym(s):

(3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone

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About This Item

Empirical Formula (Hill Notation):
C18H18ClN3O3
CAS Number:
431996-53-1
Molecular Weight:
359.81
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100

Key Documents

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SMILES string

Clc1c(ccc(c1)C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-])C

InChI

1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3

InChI key

PNECWWUOUHGWQG-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.
Filastatin is an inhibitor of Candida albicans surface binding, morphology transition and biofilm formation.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
103M4741V

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