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Merck
CN

SML0948

KY02111

≥98% (HPLC)

Synonym(s):

N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxy-benzenepropanamide

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About This Item

Empirical Formula (Hill Notation):
C18H17ClN2O3S
CAS Number:
Molecular Weight:
376.86
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

[s]1c2c(nc1NC(=O)CCc3cc(c(cc3)OC)OC)ccc(c2)Cl

InChI

1S/C18H17ClN2O3S/c1-23-14-7-3-11(9-15(14)24-2)4-8-17(22)21-18-20-13-6-5-12(19)10-16(13)25-18/h3,5-7,9-10H,4,8H2,1-2H3,(H,20,21,22)

InChI key

LXFKEVQQSKQXPR-UHFFFAOYSA-N

Biochem/physiol Actions

KY02111 promotes differentiation of human pluripotent stem cells (hPSCs) to cardiomyocytes by inhibiting WNT signaling in hPSCs in a manner that is distinct from that of previously studied WNT inhibitors. The substantial (98%) differentiation of hPSCs to cardiomyocytes with KY02111 is achieved in xeno-free and cytokine-free conditions.
KY02111 promotes differentiation of human pluripotent stem cells (hPSCs) to cardiomyocytes by inhibiting WNT signaling in hPSCs.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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