SML0988
CCCI-01
≥98% (HPLC)
Synonym(s):
5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide
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About This Item
Empirical Formula (Hill Notation):
C11H9N3O4
CAS Number:
Molecular Weight:
247.21
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
[N+](=O)([O-])c1[o]c(cc1)C(=O)NCc2cnccc2
InChI
1S/C11H9N3O4/c15-11(9-3-4-10(18-9)14(16)17)13-7-8-2-1-5-12-6-8/h1-6H,7H2,(H,13,15)
InChI key
OBZHOVWNZIVCCZ-UHFFFAOYSA-N
Biochem/physiol Actions
CCCI-01 iinduces the fomation of multipolar spindles in cancer cells.
CCCI-01 induces the fomation of multipolar spindles in cancer cells containing multiple, or supernumerary centromeres. CCCI-01 leads to centromere declustering, disruption of cell cycle and apoptsis in BT-549 breast cancer cells without affecting bipolar spindles in normal primary human mammary epithelial cells.
Features and Benefits
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Articles
Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.
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