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Merck
CN

SML0988

CCCI-01

≥98% (HPLC)

Synonym(s):

5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide

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About This Item

Empirical Formula (Hill Notation):
C11H9N3O4
CAS Number:
Molecular Weight:
247.21
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

[N+](=O)([O-])c1[o]c(cc1)C(=O)NCc2cnccc2

InChI

1S/C11H9N3O4/c15-11(9-3-4-10(18-9)14(16)17)13-7-8-2-1-5-12-6-8/h1-6H,7H2,(H,13,15)

InChI key

OBZHOVWNZIVCCZ-UHFFFAOYSA-N

Biochem/physiol Actions

CCCI-01 iinduces the fomation of multipolar spindles in cancer cells.
CCCI-01 induces the fomation of multipolar spindles in cancer cells containing multiple, or supernumerary centromeres. CCCI-01 leads to centromere declustering, disruption of cell cycle and apoptsis in BT-549 breast cancer cells without affecting bipolar spindles in normal primary human mammary epithelial cells.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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