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Merck
CN

SML1025

Lorcainide hydrochloride

≥98% (HPLC)

Synonym(s):

Lorcamide hydrochloride, N-(4-Chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-benzeneacetamide hydrochloride, R15889 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H27ClN2O · HCl
CAS Number:
58934-46-6
Molecular Weight:
407.38
UNSPSC Code:
12352200
EC Number:
261-504-6
NACRES:
NA.77

Key Documents

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SMILES string

Clc1ccc(cc1)N(C3CCN(CC3)C(C)C)C(=O)Cc2ccccc2.Cl

InChI key

FSFSWNBDCJVFGI-UHFFFAOYSA-N

InChI

1S/C22H27ClN2O.ClH/c1-17(2)24-14-12-21(13-15-24)25(20-10-8-19(23)9-11-20)22(26)16-18-6-4-3-5-7-18;/h3-11,17,21H,12-16H2,1-2H3;1H

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 10 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

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Biochem/physiol Actions

Lorcainide is a Class 1c antiarrhythmic agent that blocks open fast acting voltage-gated sodium channels (subtype Nav1.5).
Lorcainide is a Class 1c antiarrhythmic agent that blocks open fast acting voltage-gated sodium channels (subtype Nav1.5). Data shows that Lorcainide is a potent, selective antagonists/inverse agonists of human and rat H3 histamine receptors.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000190938
0000190938
054M4722V

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