SML1052
2-D08
≥98% (HPLC)
Synonym(s):
2′,3′,4′-trihydroxy-flavone, 2-(2,3,4-Trihydroxyphenyl)-4H-1-Benzopyran-4-one
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About This Item
Empirical Formula (Hill Notation):
C15H10O5
CAS Number:
Molecular Weight:
270.24
UNSPSC Code:
12352200
NACRES:
NA.77
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
[o]1c2c([c](cc1c3c(c(c(cc3)O)O)O)=O)cccc2
InChI
1S/C15H10O5/c16-10-6-5-9(14(18)15(10)19)13-7-11(17)8-3-1-2-4-12(8)20-13/h1-7,16,18-19H
InChI key
JJAXTFSPCLZPIW-UHFFFAOYSA-N
Application
2-D08 has been used as a small ubiquitin-like modifier (SUMO)ylation inhibitor.
Biochem/physiol Actions
2-D08 is a potent and cell-permeable inhibitor of sumoylation that block the transfer of SUMO (small ubiquitin-like modifier) from the E2 enzyme (Ubc9) thioester conjugate to the substrate.
2-D08 is a potent and cell-permeable inhibitor of sumoylation.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML1052-25MG | 04061833224861 |
| SML1052-5MG | 04061833224878 |