Key Documents

View All Documentation

SML1059

MMB-4

Name: MMB-4
Brand: SIGMA

≥98% (HPLC), cholinesterases reactivator, powder

Synonym(s):

1,1′-Methylenebis[4-[(hydroxyimino)methyl]-pyridinium dibromide

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₄N₄O₂· 2Br

CAS Number:

2058-89-1

Molecular Weight:

418.08

UNSPSC Code:

12352200

PubChem Substance ID:

329825642

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Product Name

MMB-4, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

light yellow to light brown

solubility

H₂O: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O/N=C/C1=CC=[N+](C[N+]2=CC=C(/C=N\O)C=C2)C=C1.[Br-].[Br-]

InChI

1S/C13H12N4O2.2BrH/c18-14-9-12-1-5-16(6-2-12)11-17-7-3-13(4-8-17)10-15-19;;/h1-10H,11H2;2*1H

InChI key

ZKQNRRLCBJUEBC-UHFFFAOYSA-N

Related Categories

Bioactive Small Molecules

Biochem/physiol Actions

MMB-4 is also called as 1,1′-Methylenebis{4-[(hydroxyimino)methyl]pyridinium) dichloride. It serves as a promising antidote for organophosphate poisoning.

MMB-4 is an oxime that can reactivate cholinesterases that have been inactivated by exposure to organophosphates such as sarin or soman. Administration of MMB-4 and atropine normalizes many respiratory parameters in guinea pigs following soman inhalation.

MMB-4 is an oxime that can reactivate cholinesterases.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chromatographic separation and NMR characterization of the isomers of MMB-4, a bis-(pyridiniumaldoxime).

Patrick Macauley et al.

Journal of pharmaceutical and biomedical analysis, 49(4), 889-894 (2009-02-17)

1,1'-Methylenebis{4-[(hydroxyimino)methyl]pyridinium) dichloride (MMB-4), a promising antidote for organophosphate poisoning, has been shown by chromatography and NMR to be a mixture of geometric isomers, predominantly the E/E form. The chromatographically separated isomers have been isolated, directly characterized by NMR to be

Articles

DISCOVER Bioactive Small Molecules for Neuroscience

Global Trade Item Number

SKU	GTIN
SML1059-5MG	04061832076942
SML1059-25MG	04061832076935

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service