SML1073
BIX
≥98% (HPLC), molecular chaperone GRP78 inducer, powder
Synonym(s):
2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid, BiP protein Inducer X
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About This Item
Empirical Formula (Hill Notation):
C9H7NO3S
CAS Number:
Molecular Weight:
209.22
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Product Name
BIX, ≥98% (HPLC)
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=C(O)C=C(C(CSC#N)=O)C=C1
InChI
1S/C9H7NO3S/c10-5-14-4-9(13)6-1-2-7(11)8(12)3-6/h1-3,11-12H,4H2
InChI key
SVFLBLCWKKQKDW-UHFFFAOYSA-N
Related Categories
Application
BIX has been used in cell viability assay.
Biochem/physiol Actions
BIX (BiP protein inducer X) induces the expression of the endoplasmic reticulum chaperone protein GRP78 (glucose regulated protein 78, BiP) leading to an attenuation of the unfolded protein response. BIX protects neuronal cells and retinal cells from ER-stress induced cell death.
BIX is an inducer of molecular chaperone GRP78 (BIP, Glucose regulated protein 78).
Other Notes
air sensitive
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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