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SML1085

Retro-2

Name: Retro-2
Brand: SIGMA

≥98% (HPLC), endosome-to-Golgi retrograde transport inhibitor, powder

Synonym(s):

2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolinone

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₁₆N₂OS

CAS Number:

1429192-00-6

Molecular Weight:

320.41

UNSPSC Code:

12352200

PubChem Substance ID:

329825463

NACRES:

NA.77

MDL number:

MFCD28124399

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Product Name

Retro-2, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

O=C1C2=CC=CC=C2NC(C3=CC=C(C)S3)N1C4=CC=CC=C4

InChI

1S/C19H16N2OS/c1-13-11-12-17(23-13)18-20-16-10-6-5-9-15(16)19(22)21(18)14-7-3-2-4-8-14/h2-12,18,20H,1H3

InChI key

BOAPXDSRULBILC-UHFFFAOYSA-N

Description

Application

Retro-2 has been used to estimate retrograde trafficking of Shiga toxin subunit B (STxB)-Cy3.

Biochem/physiol Actions

Retro-2 is a non-toxic inhibitor of the endosome-to-Golgi retrograde transport that selectively protect cells from ricin, cholera toxin, and Shiga-like toxins, without affecting compartment morphology, endogenous retrograde cargos, or other trafficking steps.

Retro-2 is a non-toxic inhibitor of the endosome-to-Golgi retrograde transport.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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