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Merck
CN

SML1093

Articaine hydrochloride

≥98% (HPLC)

Synonym(s):

4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester hydrochloride, Carticaine chlorhydrate, Carticaine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H20N2O3S · HCl
CAS Number:
23964-57-0
Molecular Weight:
320.84
NACRES:
NA.77
PubChem Substance ID:
329825470
UNSPSC Code:
12352200
EC Number:
245-957-7
MDL number:
MFCD00190157

Key Documents

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InChI

1S/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H

InChI key

GDWDBGSWGNEMGJ-UHFFFAOYSA-N

SMILES string

CC1=CSC(C(OC)=O)=C1NC(C(C)NCCC)=O.Cl

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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Biochem/physiol Actions

Articaine hydrochloride helps to alleviate pain and blocks transmission of the pain signal.
Articaine is an amide local anesthetic widely used in dentistry. Articaine acts by inhibition of nerve impulse conduction by blockade of sodium channels.
Articaine is an amide local anesthetic; sodium channel blocker.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000506059
0000506059
0000320691
0000320691
0000087326

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Effects of Lidocaine and Articaine on Neuronal Survival and Recovery.
Albalawi F, et al.
Anesthesia Progress, 65(2), 82-88 (2018)
G Batinjan et al.
International journal of oral and maxillofacial surgery, 43(12), 1503-1508 (2014-10-04)
The objective of this study was to assess the impact of low-level laser therapy on wound swelling, wound temperature changes, and oral health-related quality of life (OHRQoL) after surgical removal of impacted lower third molars. Forty patients with impacted lower

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