SML1118
Hepcidin-25 (human) trifluoroacetate salt
≥95% (HPLC), iron homeostasis regulator, powder
Synonym(s):
DTHFPICIFCCGCCHRSKCGMCCKT trifluoroacetate salt, H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt, Hepc25 (human), LEAP-1 (Liver-Expressed Antimicrobial Peptide) (human) trifluoroacetate salt, PLTR (Putative Liver Tumor Regressor ) (human)
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C113H170N34O31S9 · xC2HF3O2
CAS Number:
Molecular Weight:
2789.35 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Product Name
Hepcidin-25 (human) trifluoroacetate salt, ≥95% (HPLC)
Quality Level
assay
≥95% (HPLC)
form
powder
color
white to off-white
shipped in
wet ice
storage temp.
−20°C
Biochem/physiol Actions
Hepcidin-25 is the major isoform of hepcidin. hepcidin‐25 with reticulocyte hemoglobin content (CHr) in the hepcidin‐25 plot helps to differentiate DA can be differentiated iron‐deficient anemia (IDA) from the anemia of chronic disease (ACD) and the combined state of ACD/IDA. Mutation in the hepcidin gene is associated with the development of severe juvenile hemochromatosis.
Hepcidin is the master regulator of iron homeostasis with anti-inflammatory and antimicrobial activity.
Hepcidin is the master regulator of iron homeostasis. Hepcidin is found in liver, but also widely distributed in brain, where it may play a role in preventing iron-related neurodegeneration. Hepcidin has anti-inflammatory and antimicrobial activity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Articles
DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis.
Roetto A, et al.
Nature Genetics, 33(1), 21-21 (2003)
Serum hepcidin?25 may replace the ferritin index in the Thomas plot in assessing iron status in anemic patients.
Thomas C, et al.
International Journal of Laboratory Hematology, 33(2), 187-193 (2011)
Association of prohepcidin and hepcidin-25 with erythropoietin response and ferritin in hemodialysis patients.
Kato A, et al.
American Journal of Nephrology, 28(1), 115-121 (2008)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML1118-500UG | 04061832724478 |