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Merck
CN

SML1141

Solasodine

≥95% (HPLC)

Synonym(s):

(-)-Solasodine, (3β,22α,25R)-Spirosol-5-en-3-ol, NSC 178260, NSC 179187, Purapuridine, Solancarpidine, Solasod-5-en-3β-ol, Solasod-5-en-3β-ol (7CI,8CI), Solasodin

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About This Item

Empirical Formula (Hill Notation):
C27H43NO2
CAS Number:
126-17-0
Molecular Weight:
413.64
NACRES:
NA.77
UNSPSC Code:
12352200
EC Number:
204-774-2

Key Documents

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InChI key

KWVISVAMQJWJSZ-VKROHFNGSA-N

InChI

1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1

SMILES string

C[C@@H]1[C@]2(NC[C@H](C)CC2)O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]31[H]

assay

≥95% (HPLC)

form

powder

optical activity

[α]/D -88 to -98°, c = 0.2 in methanol

color

white to beige

solubility

DMSO: 0.5 mg/mL, clear (warmed)

storage temp.

2-8°C

Quality Level

100

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Application

Solasodine has been used in viability assays.

Biochem/physiol Actions

Solasodine is a neuroprotective antioxidant glycoalkaloid of Solanum species. Solasodine increases superoxide dismutase (SOD), catalase (CAT),and glutathione (GSH) levels, while reducing lipid peroxidation (LPO) and nitric oxide (NO) levels in the brains of ischemia/reperfusion (I/R)-injury model in rats. Also, Solasonine displayed multiple activities including, anti-cancer and leishmanicidal activities.
Solasodine is a neuroprotective antioxidant; anti-cancer; and leishmanicidal.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000472680
0000472680
0000463919
0000463919
0000245582

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