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SML1161

Ki11502

≥98% (HPLC)

Synonym(s):

Ki 11502, N-[[[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]amino]thioxomethyl]-2-methyl-benzamide

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About This Item

Empirical Formula (Hill Notation):
C26H23N3O4S
CAS Number:
347155-76-4
Molecular Weight:
473.54
NACRES:
NA.77
PubChem Substance ID:
329825691
UNSPSC Code:
12352200
MDL number:
MFCD12032139
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to brown

solubility

DMSO: 20 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

S=C(NC(C1=C(C)C=CC=C1)=O)NC(C=C2)=CC=C2OC3=CC=NC4=CC(OC)=C(OC)C=C43

InChI

1S/C26H23N3O4S/c1-16-6-4-5-7-19(16)25(30)29-26(34)28-17-8-10-18(11-9-17)33-22-12-13-27-21-15-24(32-3)23(31-2)14-20(21)22/h4-15H,1-3H3,(H2,28,29,30,34)

InChI key

ZXGIBSBJQLLUEE-UHFFFAOYSA-N

Biochem/physiol Actions

Ki11502 is a potent, ATP-competitive multikinase inhibitor that is selective for PDGF receptor. Ki11502 inhibits malignant hematopoietic cells proliferation and induces their apoptosis. Ki11502 is effective against colorectal cancer SW480 cell line.
Ki11502 is a potent, ATP-competitive multikinase inhibitor.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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