SML1247
NAB2
≥98% (HPLC)
Synonym(s):
N-(2-Chlorobenzyl)-1-(2,5-dimethylphenyl)-1H-benzo[d]imidazole-5-carboxamide
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About This Item
Empirical Formula (Hill Notation):
C23H20ClN3O
CAS Number:
Molecular Weight:
389.88
UNSPSC Code:
12352200
NACRES:
NA.77
SMILES string
Clc1c(cccc1)CNC(=O)c2cc3nc[n](c3cc2)c4c(ccc(c4)C)C
InChI
1S/C23H20ClN3O/c1-15-7-8-16(2)22(11-15)27-14-26-20-12-17(9-10-21(20)27)23(28)25-13-18-5-3-4-6-19(18)24/h3-12,14H,13H2,1-2H3,(H,25,28)
InChI key
CZSLEMCYYGEGKP-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
NAB2 is a cell permeable and selective modifier of α-synuclein toxicity diverse cell types and PD neurons. NAB2 restores Rsp5/Nedd4 E3 ligase-dependent endosomal and endoplasmic reticulum–to-Golgi vesicle trafficking.
NAB2 is a cell permeable and selective modifier of α-synuclein toxicity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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