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SML1247

NAB2

≥98% (HPLC)

Synonym(s):

N-(2-Chlorobenzyl)-1-(2,5-dimethylphenyl)-1H-benzo[d]imidazole-5-carboxamide

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About This Item

Empirical Formula (Hill Notation):
C23H20ClN3O
CAS Number:
Molecular Weight:
389.88
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

Clc1c(cccc1)CNC(=O)c2cc3nc[n](c3cc2)c4c(ccc(c4)C)C

InChI

1S/C23H20ClN3O/c1-15-7-8-16(2)22(11-15)27-14-26-20-12-17(9-10-21(20)27)23(28)25-13-18-5-3-4-6-19(18)24/h3-12,14H,13H2,1-2H3,(H,25,28)

InChI key

CZSLEMCYYGEGKP-UHFFFAOYSA-N

Biochem/physiol Actions

NAB2 is a cell permeable and selective modifier of α-synuclein toxicity diverse cell types and PD neurons. NAB2 restores Rsp5/Nedd4 E3 ligase-dependent endosomal and endoplasmic reticulum–to-Golgi vesicle trafficking.
NAB2 is a cell permeable and selective modifier of α-synuclein toxicity.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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