SML1263
Arylquin 1
≥98% (HPLC)
Synonym(s):
3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine)
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About This Item
Empirical Formula (Hill Notation):
C17H16FN3
CAS Number:
Molecular Weight:
281.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20)
SMILES string
NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F
InChI key
RHAQINSYYSNKKI-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
, white to yellow to light brown
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.
Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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