SML1283
Cilastatin sodium Ready Made Solution
50 mg/mL in DMSO/H2O, 1:1
Synonym(s):
((Z)-7-[(2R)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-{[(1S)-2,2-dimethylcyclopropanecarbonyl]amino}hept-2-enoic acid
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About This Item
Empirical Formula (Hill Notation):
C16H26N2O5S
CAS Number:
Molecular Weight:
358.45
UNSPSC Code:
12352200
NACRES:
NA.77
Form:
liquid (1:1 DMSO:H2O)
form
liquid (1:1 DMSO:H2O)
Quality Segment
concentration
50 mg/mL in DMSO/H2O, 1:1
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].S(C[C@@H](N)C(=O)[O-])CCCC\C=C(/NC(=O)[C@@H]1C(C1)(C)C)\C(=O)O
InChI
1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11-;/m1./s1
InChI key
QXPBTTUOVWMPJN-VQAYNFQASA-M
Biochem/physiol Actions
Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases.
Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases. By this action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
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