Skip to Content
Merck
CN

Key Documents

View All Documentation

SML1286

Fumonisin B1 Ready Made Solution

(Fusarium moniliforme), 1 mg/mL in DMSO

Synonym(s):

(2S,2′S)-2,2′-{[(5S,6R,7R,9R,11S,16R,18S,19S)-19-amino-11,16,18-trihydroxy-5,9-dimethylicosane-6,7-diyl]bis[oxy(2-oxoethane-2,1-diyl)]}disuccinic acid, Macrofusin

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C34H59NO15
CAS Number:
116355-83-0
Molecular Weight:
721.83
UNSPSC Code:
12352200
NACRES:
NA.77
Form:
DMSO solution
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

200

biological source

(Fusarium moniliforme)

form

DMSO solution

concentration

1 mg/mL in DMSO

shipped in

dry ice

storage temp.

−20°C

SMILES string

N[C@H]([C@@H](O)C[C@H](O)CCCC[C@H](O)C[C@H](C[C@@H](OC(=O)C[C@H](CC(=O)O)C(=O)O)[C@H](OC(=O)C[C@H](CC(=O)O)C(=O)O)[C@H](CCCC)C)C)C

InChI

1S/C34H59NO15/c1-5-6-9-20(3)32(50-31(44)17-23(34(47)48)15-29(41)42)27(49-30(43)16-22(33(45)46)14-28(39)40)13-19(2)12-24(36)10-7-8-11-25(37)18-26(38)21(4)35/h19-27,32,36-38H,5-18,35H2,1-4H3,(H,39,40)(H,41,42)(H,45,46)(H,47,48)/t19-,20+,21+,22+,23+,24+,25-,26+,27-,32-/m1/s1

InChI key

UVBUBMSSQKOIBE-ZWKVXHQASA-N

General description

Fumonisin B1 is a mycotoxin found in the fungus Fusarium moniliforme. This toxin can also be obtained from corn infected with the same fungus. Fumonisin B1 shares similarities with sphingosine and okadaic acid (OA).

Application

Fumonisin B1 from Fusarium moniliforme has been used: as a standard in the analysis of mycotoxins in caecal content obtained from adult pigs, in the study of the effect of fumonisin B1 on the metabolism of prion protein (PrP) isoforms and the synthesis of scrapie prion protein PrPSc, and in the study of the toxic effects of fumonisin B1 on explants obtained from pig jejunum.

Biochem/physiol Actions

Fumonisin B1 is a fungal metabolite that acts as a hepatocarcinogen and causes hepatotoxicity in rats. In horses, Fumonisin B1 causes leukoencephalitis, and in pigs, it causes pulmonary edema syndrome. In China and southern parts of Africa, Fumonisin B1 is linked with high incidence of esophageal cancer in humans. Fumonisin B1 acts as an inhibitor of sphingosine N-acyltransferase enzyme.
Fungal metabolite believed to cause leukoencephalomalacia in horses.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F

flash_point_c

87 °C

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library