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Merck
CN

SML1335

Pidotimod

≥98% (HPLC)

Synonym(s):

(4R)-3-(5-Oxo-L-prolyl)-1,3-thiazolidine-4-carboxylic acid, (R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid, (R)-3-[(S)-(5-Oxo-2-pyrrolidinyl) carbonyl]-thiazolidine-4-carboxylic acid, 3-L-Pyroglutamyl-L-thiaziolidine-4carboxylic acid, PGT/1A

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About This Item

Empirical Formula (Hill Notation):
C9H12N2O4S
CAS Number:
121808-62-6
Molecular Weight:
244.27
NACRES:
NA.77
PubChem Substance ID:
329825793
UNSPSC Code:
12352200
MDL number:
MFCD00867583

Key Documents

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InChI

1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1

SMILES string

OC([C@@H]1CSCN1C([C@H]2NC(CC2)=O)=O)=O

InChI key

UUTKICFRNVKFRG-WDSKDSINSA-N

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -135 to -155°, c = 1 in 6 M HCl

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

Pidotimod is a dipeptide immunostimulant with biological activity on both the adaptive and the innate immune responses. Pidotimod has been reported to modulate airway epithelial cells functions involved in host-virus interaction possibly through NF-kB activation, promote functional maturation of dendritic cells, and facilitate M2 macrophage polarization and function. Pidotimod has been investigated for use to increase response to recurrent respiratory infections primarily in children.
Pidotimod is a dipeptide immunostimulant.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000530234
0000530234
0000530236
0000530236
0000158062

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