SML1370
A-779 trifluoroacetate salt
≥98% (HPLC)
Synonym(s):
A779 trifluoroacetate salt, Asp1-Arg2-Val3-Tyr4-Ile5-His6-D-Ala7, D-Ala7-Ang-(1-7), DRVYIHA (Modification: Ala-7 = D-Ala), DRVYIHa trifluoroacetate salt, H-Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH trifluoroacetate salt, [7-D-ALA]-angiotensin-(1-7) trifluoroacetate salt
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About This Item
Empirical Formula (Hill Notation):
C39H60N12O11 · xC2HF3O2
CAS Number:
Molecular Weight:
872.97 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
lyophilized powder
Quality Segment
assay
≥98% (HPLC)
form
lyophilized powder
color
white to off-white
shipped in
wet ice
storage temp.
−20°C
Biochem/physiol Actions
This blocking angiotensin action affects cardiovascular function.
A-779 (D-Ala7-Ang-(1-7)) is a potent and selective antagonist of angiotensin (1-7), an endogenous peptide that acts through activation of a non-AT1, non-AT2 receptor, Mas, and opposes the activity of angiotensin. A-779 has an IC50 of 0.3 nM for Mas with negligible affinity for either AT1R or AT2R.
A-779 is a potent and selective antagonist of angiotensin (1-7).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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