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Merck
CN

SML1374

Alamandine trifluoroacetate salt

≥98% (HPLC)

Synonym(s):

(Ala¹)-Angiotensin I/II (1-7) trifluoroacetate salt, ARVYIHP trifluoroacetate salt, Angiotensin A (1-7) trifluoroacetate salt, H-Ala-Arg-Val-Tyr-Ile-His-Pro-OH trifluoroacetate salt, L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-Proline trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C40H62N12O9 · xC2HF3O2
CAS Number:
Molecular Weight:
855.00 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
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assay

≥98% (HPLC)

form

powder

color

white to beige

shipped in

wet ice

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Alamandine is an endogenous heptapeptide that can be formed from angiotensin A by angiotensin converting enzyme-2 or directly from angiotensin-(1–7) by decarboxylation of its aspartate residue. Alamandine′s activity is similar to Ang-(1–7) rather than that of angiotensin II or angiotensin A. However, Alamandine acts at a different receptor, the Mas-related receptor, MrgD. Alamandine causes vasodilation, and has antifibrosis and antihypertensive activity.
Alamandine is an endogenous heptapeptide with similar activity to Angitensin (1-7), but acting at a different receptor, the Mas-related receptor, MrgD.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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