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About This Item
Empirical Formula (Hill Notation):
C22H26O4
CAS Number:
Molecular Weight:
354.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Product Name
Seratrodast, ≥98% (HPLC)
InChI
1S/C22H26O4/c1-14-15(2)22(26)20(16(3)21(14)25)18(17-10-6-4-7-11-17)12-8-5-9-13-19(23)24/h4,6-7,10-11,18H,5,8-9,12-13H2,1-3H3,(H,23,24)
SMILES string
O=C(C(C)=C1C)C(C)=C(C(CCCCCC(O)=O)C2=CC=CC=C2)C1=O
InChI key
ZBVKEHDGYSLCCC-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 25 mg/mL, clear
storage temp.
2-8°C
Quality Level
Gene Information
human ... TBXA2R(6915)
Related Categories
Biochem/physiol Actions
Seratrodast is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist with anti-asthmatic activity.
Seratrodast is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist with anti-asthmatic activity. Seratrodast inhibits the bronchconstriction induced by leukotriene D4 (LTD4), and platelet activating factor (PAF) with a long duration of action.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Margarita Rosa Romero-Imbachi et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 240, 108939-108939 (2020-11-10)
Centruroides margaritatus scorpion stings are common in Colombia. However, the cardiovascular toxicity of the venom has not been clarified. To study the effect and mechanisms of action of the complete venom of C. margaritatus (CmV) on the murine cardiovascular system.
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