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SML1391

Olmesartan medoxomil

≥98% (HPLC), Angiotensin II Type I receptor blocker, powder

Synonym(s):

4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, CS-866

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About This Item

Empirical Formula (Hill Notation):
C29H30N6O6
CAS Number:
144689-63-4
Molecular Weight:
558.59
UNSPSC Code:
12352200
PubChem Substance ID:
329825839
NACRES:
NA.77
MDL number:
MFCD00944911
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

Olmesartan medoxomil, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

CCCC1=NC(C(O)(C)C)=C(C(OCC2=C(C)OC(O2)=O)=O)N1CC(C=C3)=CC=C3C4=CC=CC=C4C5=NN=NN5

InChI

1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34)

InChI key

UQGKUQLKSCSZGY-UHFFFAOYSA-N

Gene Information

human ... AGTR1(185)

Biochem/physiol Actions

Olmesartan medoxomil is considered as an antihypertensive agent. It is an angiotensin 2 type 1 antagonist receptor. It is a prodrug which releases the parent compound olmesartan after ingestion. Olmesartan is ejected via kidney and liver. In humans, olmesartan protects renal and cardiovascular systems. This drug may be used in the treatment of hypertension.
Olmesartan medoxomil is a selective Angiotensin II Type I receptor blocker and antihypertensive drug. Olmesartan medoxomil is converted enzymatically to the active form olmesartan.

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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