SML1402
TCID
≥98% (HPLC)
Synonym(s):
4,5,6,7-Tetrachloro-1,3-indandione, 4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione, CID 2729042, UCH-L3 Inhibitor
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About This Item
Empirical Formula (Hill Notation):
C9H2Cl4O2
CAS Number:
Molecular Weight:
283.92
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Product Name
TCID, ≥98% (HPLC)
InChI
1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2
SMILES string
O=C1CC(C2=C(Cl)C(Cl)=C(Cl)C(Cl)=C21)=O
InChI key
IDLAOWFFKWRNHB-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to light brown
solubility
DMSO: 5 mg/mL, clear
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
TCID is a cell penetrant potent and specific inhibitor of UCH-L3 (Ubiquitin carboxyl-terminal hydrolase isozyme L3). TCID is used to distinguish between UCH-L1 and UCH-L3 activities in cells.
TCID is a cell penetrant potent and specific inhibitor of UCH-L3.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Anurag Rathore et al.
Scientific reports, 10(1), 5350-5350 (2020-03-27)
The major barrier to a HIV-1 cure is the persistence of latent genomes despite treatment with antiretrovirals. To investigate host factors which promote HIV-1 latency, we conducted a genome-wide functional knockout screen using CRISPR-Cas9 in a HIV-1 latency cell line
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