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SML1448

Cycloastragenol

≥98% (HPLC)

Synonym(s):

Astramembrangenin, Cyclosieversigenin, Cyclosiversigenin, GRN510, TAT2, (3β,6α,16β,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol, Cyclogalegigenin

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About This Item

Empirical Formula (Hill Notation):
C30H50O5
CAS Number:
78574-94-4
Molecular Weight:
490.72
NACRES:
NA.77
PubChem Substance ID:
329825888
UNSPSC Code:
12352200
MDL number:
MFCD24849201
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +45 to +60°, c = 1 in methanol

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

C[C@]1(O[C@H](C(O)(C)C)CC1)[C@@]2([H])[C@@H](O)C[C@@]3(C)[C@]4([H])C[C@H](O)[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C6)[C@]46CC[C@@]32C

InChI

1S/C30H50O5/c1-24(2)20(33)8-11-30-16-29(30)13-12-26(5)23(28(7)10-9-21(35-28)25(3,4)34)18(32)15-27(26,6)19(29)14-17(31)22(24)30/h17-23,31-34H,8-16H2,1-7H3/t17-,18-,19-,20-,21-,22-,23-,26+,27-,28+,29-,30+/m0/s1

InChI key

WENNXORDXYGDTP-UOUCMYEWSA-N

General description

Cycloastragenol is isolated from Astragalus species.

Biochem/physiol Actions

Cycloastragenol is an aglycone of astragaloside IV isolated from Astragalus species that exhibits anti-inflammatory properties and promotes and wound gap closure. Cycloastragenol enhances the antiviral response in human CD8+ T-lymphocytes. Cycloastragenol induces telomerase activity and induces CREB (cAMP response element binding) activation in human neonatal keratinocytes, PC12 cells, and primary neurons.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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