SML1461
Kyotorphin acetate salt
≥98% (HPLC)
Synonym(s):
(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid acetate salt, KTP, L-tyrosyl-L-arginine acetate salt, Tyr-Arg acetate salt, Tyrosyl-Arginine acetate salt
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About This Item
Empirical Formula (Hill Notation):
C15H23N5O4 · xC2H4O2
CAS Number:
Molecular Weight:
337.37 (free base basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
NC(NCCC[C@@H](C(O)=O)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)=N.C
InChI
1S/C15H23N5O4.CH4/c16-11(8-9-3-5-10(21)6-4-9)13(22)20-12(14(23)24)2-1-7-19-15(17)18;/h3-6,11-12,21H,1-2,7-8,16H2,(H,20,22)(H,23,24)(H4,17,18,19);1H4/t11-,12-;/m0./s1
InChI key
KTMKVRFTDZZFFE-FXMYHANSSA-N
Biochem/physiol Actions
Kyotorphin is a neuroactive dipeptide (Tyr-Arg) shown to have analgesic, neuroprotective, and neuromodulatory properties. It is synthesized in nerve terminals and found in the brain and in cerebro-spinal fluid (CSF). Kyotorphin indirectly stimulates opioid receptors by releasing methionine enkephalin (met-enkephalin). CSF levels are lower in patients with persistent pain and in patients with Alzheimer′s disease.
Neuroactive dipeptide
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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