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Merck
CN

SML1502

Pyrazofurin

≥98% (HPLC), OMP decarboxylase inhibitor, powder

Synonym(s):

4-Hydroxy-5-β-D-ribofuranosyl-1H-pyrazole-3-carboxamide, Pirazofurin, Pyrazomycin

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About This Item

Empirical Formula (Hill Notation):
C9H13N3O6
CAS Number:
Molecular Weight:
259.22
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

Pyrazofurin, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -49 to -39°, c = 0.5 in H2O

color

white to light brown

solubility

H2O: 5 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H](O)[C@H](C2=NNC(C(N)=O)=C2O)O[C@@H]1CO

InChI

1S/C9H13N3O6/c10-9(17)4-6(15)3(11-12-4)8-7(16)5(14)2(1-13)18-8/h2,5,7-8,12-14,16-17H,1,10H2/b9-4-/t2-,5-,7-,8+/m1/s1

InChI key

CUVZEMGCUKKNOR-LNTXVZDSSA-N

Biochem/physiol Actions

Pyrazofurin serves as an effective drug against HIV (human immuno virus), vaccinia virus, West Nile viral infection.
Pyrazofurin is an orotidine-5′-monophosphate decarboxylase (ODCase, OMP decarboxylase) inhibitor that exhibit potent antiviral, anti-malarial and anti-trypanosomes activities.
Pyrazofurin is an orotidine-5′-monophosphate decarboxylase (ODCase, OMP decarboxylase) inhibitor.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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