SML1544
VPC-14228
≥98% (HPLC)
Synonym(s):
2-Morpholino-4-phenylthiazole, 4-(4-Phenyl-2-thiazolyl)-morpholine, 4-(4-Phenylthiazol-2-yl)morpholine
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About This Item
Empirical Formula (Hill Notation):
C13H14N2OS
CAS Number:
Molecular Weight:
246.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
InChI
1S/C13H14N2OS/c1-2-4-11(5-3-1)12-10-17-13(14-12)15-6-8-16-9-7-15/h1-5,10H,6-9H2
SMILES string
C1(N2CCOCC2)=NC(C3=CC=CC=C3)=CS1
InChI key
MRNNJVNMXOZEQC-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR) that binds to AR DNA-binding domain (AR DBD). Apparently VPC-14228 blocks the transcriptional activity of constitutively active AR splice variants.
VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR).
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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