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SML1544

VPC-14228

≥98% (HPLC)

Synonym(s):

2-Morpholino-4-phenylthiazole, 4-(4-Phenyl-2-thiazolyl)-morpholine, 4-(4-Phenylthiazol-2-yl)morpholine

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About This Item

Empirical Formula (Hill Notation):
C13H14N2OS
CAS Number:
19983-28-9
Molecular Weight:
246.33
NACRES:
NA.77
PubChem Substance ID:
329825954
UNSPSC Code:
51111800
MDL number:
MFCD00628805
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

C1(N2CCOCC2)=NC(C3=CC=CC=C3)=CS1

InChI

1S/C13H14N2OS/c1-2-4-11(5-3-1)12-10-17-13(14-12)15-6-8-16-9-7-15/h1-5,10H,6-9H2

InChI key

MRNNJVNMXOZEQC-UHFFFAOYSA-N

Biochem/physiol Actions

VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR) that binds to AR DNA-binding domain (AR DBD). Apparently VPC-14228 blocks the transcriptional activity of constitutively active AR splice variants.
VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR).

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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