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SML1591

Buclizine dihydrochloride

≥98% (HPLC)

Synonym(s):

1-(p-Chloro-α-phenylbenzyl)-4-(p-tert-butylbenzyl)piperazine, 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)-diethylenediamine hydrochloride, 1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-piperazine dihydrochloride, Buclina, Longifene, Posdel, UCB-4445, Vibazine, Vibazine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C28H33ClN2 · 2HCl
CAS Number:
129-74-8
Molecular Weight:
505.95
UNSPSC Code:
12352200
PubChem Substance ID:
329825975
NACRES:
NA.77
MDL number:
MFCD00242700
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 1 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[Cl-].[Cl-].Clc1ccc(cc1)C(N3CCN(CC3)Cc4ccc(cc4)C(C)(C)C)c2ccccc2.[H+].[H+]

InChI

1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H

InChI key

SDBHDSZKNVDKNU-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

Biochem/physiol Actions

Buclizine is a piperazine antihistamine and anticholinergic that exerts its antiemetic and antimotion sickness effects.
Histamine H1 receptor antagonist

Storage Class

11 - Combustible Solids

wgk

WGK 3

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