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About This Item
Empirical Formula (Hill Notation):
C28H33ClN2 · 2HCl
CAS Number:
Molecular Weight:
505.95
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
SMILES string
[Cl-].[Cl-].Clc1ccc(cc1)C(N3CCN(CC3)Cc4ccc(cc4)C(C)(C)C)c2ccccc2.[H+].[H+]
InChI
1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H
InChI key
SDBHDSZKNVDKNU-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 1 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
Gene Information
human ... HRH1(3269)
Biochem/physiol Actions
Buclizine is a piperazine antihistamine and anticholinergic that exerts its antiemetic and antimotion sickness effects.
Histamine H1 receptor antagonist
Storage Class
11 - Combustible Solids
wgk
WGK 3
Regulatory Information
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