Skip to Content
Merck
CN

Key Documents

View All Documentation

SML1613

CC-401 dihydrochloride

≥95% (HPLC)

Synonym(s):

1-[5-(1H-1,2,4-Triazol-5-yl)-1H-indazol-3-yl]-3-(2-piperidinoethoxy)benzene dihydrochloride, 3-(3-(2-(Piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-3-yl)-1H-indazole dihydrochloride, 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-iIndazole dihydrochloride, CC 401, CC401, CID 10430360

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C22H24N6O · 2HCl
CAS Number:
1438391-30-0
Molecular Weight:
461.39
NACRES:
NA.77
PubChem Substance ID:
329825499
UNSPSC Code:
12352200
MDL number:
MFCD21364765
Assay:
≥95% (HPLC)
Form:
powder
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

100

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

H2O: 10 mg/mL, clear

storage temp.

−20°C

SMILES string

[H]Cl.C1(C2=NC=NN2)=CC3=C(NN=C3C4=CC=CC(OCCN5CCCCC5)=C4)C=C1

InChI

1S/C22H24N6O.ClH/c1-2-9-28(10-3-1)11-12-29-18-6-4-5-16(13-18)21-19-14-17(22-23-15-24-27-22)7-8-20(19)25-26-21;/h4-8,13-15H,1-3,9-12H2,(H,25,26)(H,23,24,27);1H

InChI key

OIBVXKYKWOUGAO-UHFFFAOYSA-N

Biochem/physiol Actions

CC-401 is a cell penetrant, potent and selective c-Jun N terminal kinase (JNK) inhibitor that blocks JNK signaling in the rat obstructed kidney and inhibits renal fibrosis in the unilateral ureteral obstruction model. CC-401 in combination with chemotherapy exhibits synergism in colon cancer cell lines.
CC-401 is a cell penetrant, potent and selective c-Jun N terminal kinase (JNK) inhibitor.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library