SML1623
MSP-3
≥98% (HPLC)
Synonym(s):
N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide
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About This Item
Empirical Formula (Hill Notation):
C16H19NO3S
CAS Number:
Molecular Weight:
305.39
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
oil
Quality Segment
assay
≥98% (HPLC)
form
oil
color
white to beige
storage temp.
room temp
SMILES string
O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
InChI
1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
InChI key
HCUVEUVIUAJXRB-UHFFFAOYSA-N
Biochem/physiol Actions
MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.
TRPV1 agonist protective against oxidative stress
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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