SML1623
MSP-3
≥98% (HPLC)
Synonym(s):
N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide
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About This Item
Empirical Formula (Hill Notation):
C16H19NO3S
CAS Number:
Molecular Weight:
305.39
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
SMILES string
O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
InChI
1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
InChI key
HCUVEUVIUAJXRB-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
oil
color
white to beige
storage temp.
room temp
Quality Level
Related Categories
Biochem/physiol Actions
MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.
TRPV1 agonist protective against oxidative stress
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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