Skip to Content
Merck
CN

SML1625

Gemifloxacin mesylate

≥98% (HPLC)

Synonym(s):

7-(4-Aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1, 4-dihydro-1,8-naphthyridine-3-carboxylic acid mesylate, 7-[(4Z)-3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid monomethanesulfonate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C18H20FN5O4 · CH4O3S
CAS Number:
210353-53-0
Molecular Weight:
485.49
NACRES:
NA.77
PubChem Substance ID:
329825509
UNSPSC Code:
12352200
MDL number:
MFCD08277637

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

color

white to light brown

InChI key

JIYMVSQRGZEYAX-CWUUNJJBSA-N

SMILES string

CS(=O)(O)=O.OC(C1=CN(C2CC2)C3=NC(N4C/C(C(CN)C4)=N\OC)=C(F)C=C3C1=O)=O

InChI

1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+;

assay

≥98% (HPLC)

form

powder

solubility

H2O: 10 mg/mL, clear

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

Gemifloxacin is a broad-spectrum quinolone antibacterial.
Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Muta. 2 - Repr. 2 - STOT RE 2

target_organs

Liver

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000463175
0000463175
0000189452
0000189451
0000189452

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service