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About This Item
Empirical Formula (Hill Notation):
C18H16F3NO3
CAS Number:
Molecular Weight:
351.32
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 25 mg/mL, clear
storage temp.
room temp
SMILES string
O=C(NC1=CC=C(C(F)(F)F)C=C1)/C=C/C2=CC=C(OC)C(OC)=C2
InChI
1S/C18H16F3NO3/c1-24-15-9-3-12(11-16(15)25-2)4-10-17(23)22-14-7-5-13(6-8-14)18(19,20)21/h3-11H,1-2H3,(H,22,23)/b10-4+
InChI key
KFWWXJZNIMFFRO-ONNFQVAWSA-N
Biochem/physiol Actions
TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice. Apparently TFCA binds to the LXR? ligand binding domain and induces interaction with NCoR corepressor.
TFCA is a Liver X receptor α (LXRα) antagonist.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML1626-5MG | 04061833058640 |
| SML1626-25MG | 04061833058633 |
