SML1646
ZQ-16
≥98% (HPLC)
Synonym(s):
2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone
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About This Item
Empirical Formula (Hill Notation):
C10H16N2O2S
CAS Number:
Molecular Weight:
228.31
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
SMILES string
CCCCCCSC1=NC(O)=CC(O)=N1
InChI
1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14)
InChI key
UYXOAKRMLQKLQX-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
room temp
Quality Level
Biochem/physiol Actions
ZQ-16 is a potent and selective agonist for medium-chain free fatty acid receptor GPR84 (G protein-coupled receptor 84). ZQ-16 activates GPR84-mediated calcium mobilization, inhibition of cAMP accumulation, phosphorylation of ERK1/2, receptor desensitization and internalization, and receptor-β-arrestin interaction.
ZQ-16 is a potent and selective agonist for medium-chain free fatty acid receptor GPR84.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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