SML1709
K6PC-5
≥98% (HPLC)
Synonym(s):
2-Hexyl-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-3-oxo-decanamide, K 6PC5;, N-(1,3-Dihydroxypropyl)-2-hexyl-3-oxo-decanamide
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About This Item
Empirical Formula (Hill Notation):
C19H37NO4
CAS Number:
Molecular Weight:
343.50
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
InChI key
CGYVFCHCRBGGJG-UHFFFAOYSA-N
SMILES string
O=C(CCCCCCC)C(CCCCCC)C(NC(CO)CO)=O
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
−20°C
Quality Level
Related Categories
Biochem/physiol Actions
K6PC-5 is a potent and selective sphingosine kinase 1 (SphK1 or SK1) activator that increases keratin 1 and involucrin expression in normal human epidermal keratinocytes cultured in vitro. K6PC-5 promotes differentiation and proliferation of keratinocytes via intracellular Ca2+ signaling.
K6PC-5 is a potent and selective sphingosine kinase 1 (SphK1 or SK1) activator.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Michaela T Reichmann et al.
The Journal of clinical investigation, 131(15) (2021-06-16)
Tuberculosis (TB) is a persistent global pandemic, and standard treatment for it has not changed for 30 years. Mycobacterium tuberculosis (Mtb) has undergone prolonged coevolution with humans, and patients can control Mtb even after extensive infection, demonstrating the fine balance
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