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SML1714

DCAI

≥95% (HPLC)

Synonym(s):

2-(4,6-Dichloro-2-methyl-1h-indol-3-yl)ethanamine, 4,6-Dichloro-2-methyl-3-aminoethylindole

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About This Item

Empirical Formula (Hill Notation):
C11H12Cl2N2
CAS Number:
Molecular Weight:
243.13
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
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Quality Segment

assay

≥95% (HPLC)

form

powder

color

white to brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

Clc1c2c([nH]c(c2CCN)C)cc(c1)Cl

InChI

1S/C11H12Cl2N2/c1-6-8(2-3-14)11-9(13)4-7(12)5-10(11)15-6/h4-5,15H,2-3,14H2,1H3

InChI key

JCTJISIFGZHOFY-UHFFFAOYSA-N

Biochem/physiol Actions

DCAI, an Inactive Ras, is bound to a GDP and activated by SOS (son of sevenless, among others), which converts it to the active GTP form. DCAI is a known binder to Ras, which inhibits SOS nucleotide exchange, inhibiting Ras activation.
DCAI, an inactive Ras, is bound to a GDP and activated by SOS (son of sevenless, among others) which converts it to the active GTP form.


pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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