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Merck
CN

SML1720

ATI-2341 trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

ATI 2341 trifluoroacetate salt, N-(1-Ohexadecyl)-L-methionylglycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-α-aspartyl-L-lysyl-L-tyrosyl-L-arginyl- L-leucine, Pal-MGYQKKLRSMTDKYRL, Pal-Met-Gly-Tyr-Gln-Lys-Lys-Leu-Arg-Ser-Met-Thr-Asp-Lys-Tyr-Arg-Leu

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About This Item

Empirical Formula (Hill Notation):
C104H178N26O25S2 · xC2HF3O2
CAS Number:
Molecular Weight:
2256.82 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
film
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Quality Segment

assay

≥95% (HPLC)

form

film

color

colorless

shipped in

wet ice

storage temp.

−20°C

Biochem/physiol Actions

ATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4) that functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 does not promote β-arrestin recruitment. ATI-2341 promotes the mobilization of PMNs and HSPCs in the peripheral circulation of both mice and monkeys.
ATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4).


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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