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Merck
CN

SML1725

RTC13

≥98% (HPLC)

Synonym(s):

(5Z)-2-Amino-5-[[5-(2-nitrophenyl)-2-furanyl]methylene]-4(5H)-thiazolone, (Z)-2-Amino-5-((5-(2-nitrophenyl)furan-2-yl)methylene)thiazolidin-4-one

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About This Item

Empirical Formula (Hill Notation):
C14H9N3O4S
CAS Number:
1359825-94-7
Molecular Weight:
315.30
NACRES:
NA.77
PubChem Substance ID:
329826040
UNSPSC Code:
12352200
MDL number:
MFCD00808624

Key Documents

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InChI

1S/C14H9N3O4S/c15-14-16-13(18)12(22-14)7-8-5-6-11(21-8)9-3-1-2-4-10(9)17(19)20/h1-7H,(H2,15,16,18)/b12-7+

SMILES string

O=C1NC(S/C1=C\C2=CC=C(C3=C([N+]([O-])=O)C=CC=C3)O2)=N

InChI key

CZZAPCPWFCGOCC-KPKJPENVSA-N

assay

≥98% (HPLC)

form

powder

color

yellow to orange

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

Related Categories

Biochem/physiol Actions

RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production from transcripts containing nonsense mutations-generated PTCs, including ataxia-telangiectasia (A-T) mutated in A-T lymphoblastoid cell cultures and dystrophin in mdx Duchenne muscular dystrophy (DMD) mice-derived muscle myotubes.
RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000181653
0000181654
0000181654
0000181653
106M4751V

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