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SML1766

Diphyllin

≥98% (HPLC)

Synonym(s):

9-(1,3-Benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-naphtho[2,3-c]furan-1(3H)-one, NSC 309691

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About This Item

Empirical Formula (Hill Notation):
C21H16O7
CAS Number:
22055-22-7
Molecular Weight:
380.35
NACRES:
NA.77
PubChem Substance ID:
329826058
UNSPSC Code:
12352200
MDL number:
MFCD00808222
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

OC1=C2C(C(OC2)=O)=C(C3=CC=C(OCO4)C4=C3)C5=CC(OC)=C(OC)C=C51

InChI

1S/C21H16O7/c1-24-15-6-11-12(7-16(15)25-2)20(22)13-8-26-21(23)19(13)18(11)10-3-4-14-17(5-10)28-9-27-14/h3-7,22H,8-9H2,1-2H3

InChI key

VMEJANRODATDOF-UHFFFAOYSA-N

General description

Diphyllin, a major glycoside compound, is a plant-derived lignan. It is present in Cleistanthus collinus.

Application

Diphyllin has been used to study its antibacterial and antibiofilm activities against fish pathogens.

Biochem/physiol Actions

Diphyllin has shown potential to be used in a novel treatment for bone problems characterized by excessive resorption.
Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities.
Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities. It is a potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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