SML1770
PhiKan083 hydrochloride
≥98% (HPLC)
别名:
9-Ethyl-N-methyl-9H-Carbazole-3-methanamine hydrochloride, PK-083 hydrochloride, PK083 hydrochloride, PhiKan-083 hydrochloride
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关于此项目
经验公式（希尔记法）:
C16H18N2 · HCl
化学文摘社编号:
分子量:
274.79
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CNCC1=CC2=C(C=C1)N(CC)C3=C2C=CC=C3.[H]Cl
InChI key
IXWVUPURFWFRNE-UHFFFAOYSA-N
Biochem/physiol Actions
Mutant p53 stabilizer
PhiKan083 is a small molecule that binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.
wgk
WGK 3
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable