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SML1853

Kaempferitrin

≥97% (NMR)

Synonym(s):

3,7-Bis((6-deoxy-α-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kaempferol 3,7-dirhamnoside, Lespedin, Lespenefril, Lespenephryl

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About This Item

Empirical Formula (Hill Notation):
C27H30O14
CAS Number:
482-38-2
Molecular Weight:
578.52
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD21333499
Assay:
≥97% (NMR)
Form:
powder
Quality level:
100
Storage condition:
desiccated, protect from light
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biological source

(Cinnamomum sp.)

Quality Level

100

assay

≥97% (NMR)

form

powder

storage condition

desiccated, protect from light

color

white to beige

storage temp.

−20°C

SMILES string

OC(C=C1)=CC=C1C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(C4=C(O)C=C(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C=C4O2)=O

InChI

1S/C27H30O14/c1-9-17(30)20(33)22(35)26(37-9)39-13-7-14(29)16-15(8-13)40-24(11-3-5-12(28)6-4-11)25(19(16)32)41-27-23(36)21(34)18(31)10(2)38-27/h3-10,17-18,20-23,26-31,33-36H,1-2H3/t9-,10-,17-,18-,20+,21+,22+,23+,26-,27-/m0/s1

InChI key

PUPKKEQDLNREIM-QNSQPKOQSA-N

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Biochem/physiol Actions

Kaempferitrin is a flavonol glycoside, present in several plants, predominant in Bauhinia. It is known to stimulate insulin signaling pathway and induces glucose uptake, by mediating GLUT4 (glucose transporter 4) translocation to adipocyte membrane.. Kaempferitrin aids in lowering blood glucose level and therefore helps to improve the glycemic condition in diabetic animals.
Kaempferitrin (Lespenefril) is a naturally-occurring kaempferol glycoside with antimicrobial, antioxidant, and anti-inflammatory activities.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000463170
0000463170
0000377967
0000377967
0000167194

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Julia Cassani et al.
Molecules (Basel, Switzerland), 19(12), 21442-21461 (2014-12-24)
We evaluated the antidepressant-like effect of kaempferitrin (Km) isolated from the plant Justicia spicigera (Asteraceae), which is used in traditional medicine for relieving emotional disorders, such as "la tristeza" (sadness or dysthymia) and "el humor" (mood changes). The actions of
Discovery and Development of Antidiabetic Agents from Natural Products, 118-118 (2016)
Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes
Tzeng YM, et al.
European Journal of Pharmacology, 607(1-3), 27-34 (2009)
Medicinal and Aromatic Plants of South America: Brazil, 142-142 (2018)
Xue-Qin Ma et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 22(13), 1159-1162 (2015-11-26)
Podocarpium podocarpum (DC.), an edible and medicinal plant popularly used for the treatment of bruises and fracture in Chinese folk medicine, has been proved to possess significant antiosteoporotic effect in our latest research. Our study aimed to investigate the in
View All Related Papers

Global Trade Item Number

SKUGTIN
SML1853-1MG04061824080865
SML1853-5MG04061837107986

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